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Conduct Research Research Life

My Virtual Global Seminar Experience: Jumping in Foreign Water

In the summer of 2021, I participated in a virtual global seminar in Cyprus entitled Conflict, Borders, Multilingualism, Translation. I was particularly drawn to the idea of learning about Cyprus’ history and culture through the lens of multilingualism and translation. Personally, language has always played a key role in my understanding of identity and culture. Three languages are spoken in my home (Filipino, English, and Chinese Hokkien), and growing up in this way has made me very conscious of language-culture influences, code-switching, and nuances in connotation.

Image taken from the 
Princeton Institute for International and Regional Studies http://piirs.princeton.edu/piirs-global-seminars/2022cyprus
An aerial shot of Nicosia, the capital of Cyprus

Applying to this global seminar was a spontaneous decision; I major in MAE and am more used to spending my summers doing research and technology. However, when I read about this seminar in an email, I knew that it aligned with my personal interests in the social sciences. Because of the great time I had during the seminar, I am writing to motivate people to take advantage of the breadth of courses offered by Princeton and try studying something totally spontaneous and new!

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Conduct Research Research Life

NCBI: An Invaluable Tool for Life Sciences Classes and Research!

Have you ever come across something in class that you wish you could get a better Have you ever been wondering more about how proteins are made in the body? Or have you ever been looking for a specific type of lab experiment protocol for your independent work? If yes, then look no further than the National Center for Biotechnology Information (NCBI) website! It contains dozens of resources, some of which I have found to be very handy in my own research and school experiences. The site is tailored for students in the life-sciences field, but there is a lot of breadth in the resources available—you’ll be able to find useful tools regardless of whether you’re a MOL or CHM major, or if you’re interests lie in researching chemically synthesis mental health, or neurodegenerative diseases.

The NCBI Logo, as it appears on the website

A very useful tool on the NCBI website is Bookshelf. There is a search bar at the top of the website where you can input some topic, book title, or field name, and the program will return a variety of different reference materials relating to the query, including full scientific textbooks, book chapters, studies. On the side, there are often figures and graphs that may relate to your search. 

Some sample search results within Bookshelf if I look up “synaptic plasticity”
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Conduct Research Independent Work Present & Publish Findings Research Life

Back to the Classroom: How to Readjust to In-Person Exams

With midterms being in full swing this week, you’ve most likely started reviewing concepts and studying for these exams. However, another crucial part of the preparation process is to readjust to the in-person exam experience. After a year and a half of taking exams virtually, it is important to recognize that exams in the classroom will look and feel very different, so don’t let that take you by surprise. Whether you are studying for midterms or want to start thinking about final exams, here are a few key tips when it comes to taking exams at Princeton in person:

McDonnell A01, a large lecture hall where one of my midterms is taking place this semester
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Conduct Research Research Life

It’s Midterm Season: 6 Tips for Success on Midterms

East Pyne looks absolutely beautiful as students approach midterm season.

Midterms start this week. I know; I also had to read that twice because I could not believe it. Time is flying on campus and it has been amazing, but with everything going on it can be difficult to stay motivated and study for midterms. Nonetheless, I believe in myself and all of you reading this post! We will make it through midterms and we will succeed. Here are the tips and tricks that I am going to use to perform my best, and I hope that you can use them too:

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Conduct Research Independent Work Present & Publish Findings

Writing a Literature Review? Some Tips Before You Start

Writing the literature review section for a scientific research article can be a daunting task. This blog post is a summary of what I have personally found to best help when writing about scientific research. I hope some of these tips can help make the process an easier and more fulfilling experience!

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Conduct Research Research Life

Making Use of Office Hours

With classes in full swing, I thought I would share my thoughts on what is a woefully underused resource at Princeton: office hours. Going to office hours has been an extremely valuable tool for me in completing problem sets, studying for tests and exams, and connecting with professors. So read ahead for some advice and observations I’ve made!

Consult your department’s website or syllabus for professors’ office hour availabilities—faculty try hard to make themselves available because office hours can be a very valuable resource!
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Conduct Research Independent Work

How to Get Involved with Lab-Based Research at Princeton

As a first-year B.S.E student with little to no previous research experience, the idea of writing an eighty-page senior thesis based on my own lab-based research seemed like an extremely daunting task. Now, into the first semester of my junior year, the thought of having to write a thesis next year still seems like a challenge, although a lot less intimidating than two years ago. The main reason for this is because I have participated in multiple research-based summer internships through Princeton, which have helped me feel better prepared to do lab-based junior independent work and a senior thesis in the coming semesters.

You may also be wondering how early you can get involved with lab-based research at Princeton. Although there is certainly no pressure to do research as a first-year or sophomore if you do not want to, Princeton does make sure that opportunities are available for those who do want to be involved early. Here’s a timeline of some of the different lab-based opportunities available, and when you can start getting involved.

The scanning electron microscope in Princeton’s Imaging and Analysis Center, where I am doing research with a material science lab on campus.
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Conduct Research

Doing Research in a Pandemic, an Interview with Professor Yael Niv

For this Spring Seasonal Series, entitled Doing Research in a Pandemic, each correspondent has selected a researcher to interview about the impact of the pandemic on their research. We hope that these interviews document the nuanced ways the pandemic has affected research experiences, and serve as a resource for students and other researchers. Here, Ryan shares her interview.

Professor Niv at the Princeton Neuroscience Institute.

For this seasonal series, I decided to interview Yael Niv, a Professor in Neuroscience and Psychology at Princeton University. Professor Niv has conducted key research on reinforcement learning and decision-making and she continues to contribute to this field at her lab at the Princeton Neuroscience Institute. I decided to interview Professor Niv because I have taken two courses with her (FRS172: Our Subjective Reality and PSY338: From Animal Learning to Changing Minds) and have truly been inspired by the work she has done and the positive attitude that she brings to the classroom every day. I know that we can all learn from Professor Niv, especially at a time like right now. In our interview, we discuss the importance of hallway encounters, research opportunities during the pandemic, and the future of her lab.

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Conduct Research

Getting Involved in Research Early

As I near the end of my first two years at Princeton, I thought that it would be useful to reflect on my time here so far, and how I prepared (or often did not prepare) myself to take advantage of research and internship opportunities. As I mentioned in my last post, one of the most useful parts of my internship search this year was talking with the preceptor of one of my classes, as I had the chance to learn from the experience of an older student. Here, I thought I might try and put my own advice into practice by flipping it around: while I cannot claim to have anywhere near the same experience of our graduate counterparts, I thought that my experience might still be useful to current and future first-year students. These are some of the pieces of advice from my time here.

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Conduct Research Independent Work

Visualizing COVID-19 Mutations Using PyMOL, a University Provided Resource

These days, it seems like every day we learn of a new variant of SARS-CoV-2 (the virus that causes COVID-19). However, it’s hard to understand what a variant is and how it changes the virus. In this post, I wanted to introduce PyMOL, a program that students have access to through the University. This program can be used to see what the spike protein and its mutations actually look like.

But first, here’s some background on SARS-CoV-2: COVID-19 is a disease caused by a strain of coronavirus called SARS-CoV-2. This virus gets inside the human cells by using something called a spike protein. This spike protein binds to a receptor on the human cell called the ACE2 receptor, and this allows the virus to infiltrate the cell. The variants of SARS-CoV-2 that we keep hearing about typically have different mutations on the spike protein. In the case of the B.1.1.7 variant, which is a variant that is thought to be 30-50 percent more infectious than other variants in circulation, the mutations are at a location that allow the spike protein to bind better to the ACE2 receptor. If you bind better to the receptor, you’re better at infiltrating the cell. The spike is also the target of the vaccine and our natural immune system.

Now, let’s try and look at where these mutations actually are.

This is an illustration of the SARS-CoV-2 virus published by the CDC. The spikes are in red, labeled with a white arrow.