A Hidden iGem at Princeton

Dowon Seo '27 stands center frame holding a microphone, in front of a presentation screen describing quorum sensing. Besides him are members of the iGem team.
Dowon Seo ’27 presenting Research in Paris, France. Photo courtesy of Dowon Seo.

Princeton offers a wealth of opportunities to engage in undergraduate research. From smaller projects found in writing seminars to the ever-looming senior thesis, research is woven throughout our academic journeys. Still, outside of this mandatory exposure to research there are also unique opportunities to explore research as an undergraduate. One of the most interesting of these is the Princeton iGem team. I was able to sit down to speak with a member of this year’s team, Dowon Seo ‘27, after he returned from the annual iGem conference in Paris.

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Harmonizing Research and A Cappella: How Music Fuels My Scientific Journey

Photo of the members of the Princeton Footnotes in the year 2024-2025, taken at Rocky courtyard
Photo of the Footnotes, Princeton’s fresh low-voice a cappella group founded in 1959

Imagine standing in front of a big audience, heart racing, ready to blend your voice with others and hit the notes of an intricate a cappella arrangement. Every beat, every breath, is crucial. Every time I stand on stage or under an arch with my a cappella group, the Princeton Footnotes, I think of how similar singing and music feels to what I do in the lab. You might be thinking that singing in an a cappella group and doing research are worlds apart. However, these two passions have formed a bond in ways that I never believed possible. In fact, the creativity, collaboration, and discipline I have channeled in being a part of the Footnotes have made me a better researcher—and vice versa. 

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Field Research on the Juneau Icefield: Living the Emersonian Triangle

A Terrestrial Radar Interferometry (TRI) station overlooking Echo Glacier — a field site used by NASA as an analog environment to the moon Europa.
A Terrestrial Radar Interferometry (TRI) station overlooking Echo Glacier — a field site used by NASA as an analog environment to the moon Europa. Photo credit: Advik Eswaran.

Students across a variety of disciplines (or fields, if you will) have the opportunity to perform fieldwork at Princeton. In contrast to lab work—which involves performing experiments or analyses within a controlled on-campus environment—fieldwork takes place, well, in the field. Researchers venture out into the wide, wild world in pursuit of somehow collecting useful data from the vast webs of chaos that surround them. In my home department of the Geosciences, fieldwork is the norm: students go out to geological field camps or embark on oceanographic cruises to gather data about the raw Earth that surrounds us. However, fieldwork is truly possible in any discipline.

This past summer, I conducted my own fieldwork as part of the Juneau Icefield Research Program (JIRP). For two months, I lived and conducted glaciology research with about 40 other students, staff, and faculty on the glaciers of the Juneau Icefield—an interconnected system of over 140 glaciers spanning 1500 square miles across southern Alaska and northern Canada. It was one of the most incredible—and intellectually rewarding—experiences of my life. Here, I’ll share some stories from my time on the Icefield, contextualizing them within some broader lessons I learned about how field research operates.

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A Quick Guide to Securing Funding

This photo shows a student working in lab with his mentor.
A student working in a lab, potentially on a research project for their senior work that would greatly benefit from funding! Photo credit: Nick Donnoli.

You’ve brainstormed a great idea for your research project. You have the details of your topic all figured out, but you need some assistance with figuring out the logistics of the financial aspects that come with your great idea.  

If that’s you, here’s a quick guide on one way of securing funding as a Princeton student! 

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Why you should apply to 2024 International Internship Program (IIP)

Spotlighting the experiences of the 2023 IIP Virtual Poster Winners

Several of the winning virtual posters from the 2023 IIP Program
Several of the winning virtual posters from the 2023 IIP Program

Applications are currently open for the 2025 Summer International Internship Program (IIP)! This incredible program connects 1st, 2nd, and 3rd year students with an international institution for ~8 weeks to pursue a project that allows them to explore different careers, cultures, and workplace environments. Many of these projects empower students to take on various research endeavors, learn new research skills, and apply their research findings to make an impact on global communities. Here are several spotlights of Princeton students who shared their internship experiences and were winners of the 2023 IIP Virtual Posters. You can also view all of the poster reflections.

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Into the Unknown

Reflection on my personal experience tackling a new research paradigm

Yubi Mamiya presenting her findings on "Clinical trial simulation of ensitrelvir for SARS-CoV-2" to the Fred Hutchinson Cancer Center Infectious Disease Sciences Department.
Yubi Mamiya presenting her findings on “Clinical trial simulation of ensitrelvir for SARS-CoV-2” to the Fred Hutchinson Cancer Center Infectious Disease Sciences Department.

I’ve always believed in challenging myself to learn new methodologies and explore new fields in my research. Yet, there’s a fine balance between tackling a new challenge and feeling over your head. Reflecting on my past summer conducting a project in a completely new research paradigm, I wanted to take a moment to share my experience in the hopes of encouraging other students to be unafraid to undertake novel endeavors.

I had the life-changing opportunity to research the dose-response of the oral antiviral ensitrelvir for treating mild to moderate symptoms of SARS-CoV-2 with the Schiffer Lab starting this past June as an intern in the Fred Hutchinson Cancer Center Infectious Disease Sciences Internship Program. This project employed a very different application of my interests in healthcare and computer programming than I’d ever done before. Wide-eyed with amazement and curiosity, I delved into the fields of pharmacology, clinical trials, mathematical modeling, infectious diseases, and computational simulations. I remember learning about my project goals for the first time and thinking: “Wow, there are thousands of other students who would make a much better intern on this project”. This overwhelming imposter syndrome is something that I’ve often struggled with during my past research experiences when walking into new fields for the first time. But, thanks to the incredible mentorship of the Schiffer Lab and the tips that they shared with me, I overcame this fear and was able to grow into a more interdisciplinary and confident researcher this summer. I hope to pass on this same inspiration to other students here.

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Choosing A Lab: To Stay or To Go?

Photo meant to show students in a laboratory setting.
Students collaborating in a molecular biology laboratory. Photo credit: Matt Raspanti.

Many students at Princeton spend their summers exploring a research project or a lab internship in their field of interest. But what’s next? Maybe you really enjoyed your experience and wanted to continue. Then, you come across the question: should I stay in the same lab or join a different lab? 

This was the question I pondered when entering my sophomore year. I had an incredible summer experience as an High Meadows Environmental Institute intern in the Sigman Research Laboratory in the summer of 2023. I worked on a project that enabled my exploration of biogeochemical reconstruction via an investigation of the marine environment during a historical mass extinction through the use of a biological proxy known as foraminifera. But, where did I want to go from there? If you’re in a similar position, here are some things to keep in mind! 

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Exploring Memory: My First-Year Research Experience

The picture shows Dr. Augustin Hennings and I in the MRI control room on the C Level of Princeton Neuroscience Institute. We were monitoring the screens in one of the pilot scans.
Dr. Augustin Hennings and I in the MRI control room, C Level, PNI

It felt a little odd to begin an email with, “I wrote about your lab in my application to Princeton!” but it was the truth. Since high school, I had been fascinated by memory and its profound effects on shaping our lives, which motivated me to pursue a degree in neuroscience. Professor Kenneth Norman’s work in the Princeton Computational Memory Lab captured my attention while I was exploring Princeton’s resources for my application essays. I wrote about how I wanted to be a part of the lab and study human memory, specifically focusing on how the brain and mind can overcome the emotional consequences of trauma-based memories. After arriving at Princeton, I had been eagerly awaiting the right time to reach out to Professor Norman about getting involved in his research.

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Surf’s Up: A Guide to Internet Surfing, and other Assorted Browsing Research Skills

This image depicts a Google search of "What is research," which symbolizes the purpose of this post—i.e. figuring out how to research online.
What is research? Perhaps we can ask the Internet…

If you’re anything like me, you first thought that “research” essentially amounted to surfing the Internet. Back in the glory days of middle school, “research” meant the rewarded privilege of getting to use the laptop carts, productively using class time on googling information about our various project topics (and definitely not secretly playing games). Now, as the mature, worldly college student you now are, perhaps you think you know better. “True” academic research, the clever reader now knowingly tells themselves, is historians dusting through archival documents and scientists mixing frothy chemicals in the lab. 

Yet there’s a missing part here: a crucial element that takes us back to our elementary and middle days of excited googling. To make any significant intellectual contribution to any field, one first has to understand the current state of knowledge in that same field. To borrow the term favored by the Writing Program, we need to understand the scholarly conversation. How do we know if we’re making a contribution to something, if we don’t understand what that something is? Understanding the current state of research in a given field is a crucially important skill—really, a prerequisite—for conducting your own effective research in that field. 

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Mentorship Matters: A Summer of Research and Growth

This image shows a lab technician pipetting a clear solution into an another orange-colored solution inside a fume hood in a lab
Photo of a chem-bioengineering lab, photo credit to Iris Rubinstein.

When I first walked into the lab this summer, I thought research was all about running experiments and gathering data. What I didn’t expect was how much the people around me—the mentorship and the shared triumphs and failures—would shape so much of my learning and how I view scientific research. 

Starting a research position at a bioengineering lab over the summer was really intimidating for me, especially as an undergraduate. At the start, I felt like the most inexperienced person in a room full of graduate students, postdocs, and faculty who seem to have it all figured out. Although I’ve learned or at least seen a lot of the quantitative and qualitative components in my Chemical and Biological Engineering course, I did not have much hands-on experience and critical thinking that comes with actually doing experiments. That’s when I realized how big of a role a mentor plays.

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