Turning a Laboratory-Based Research Proposal into a Remote Project

Last spring semester, I was completing my junior independent work in a bioengineering lab on campus. My project was lab-heavy, as I was investigating the extent of DNA damage (measured as type and frequency of breaks occurring in the DNA) that occurs in persister subpopulations (cell populations with non-inherited tolerance to antibiotics) of E.Coli cells when treated with antibiotics and other DNA damaging agents. I had prepared a series of experiments to test these conditions, most of which would be performed after returning from spring break. However, those plans changed in March, when students were sent home due to the COVID-19 pandemic.


Like many other lab researchers, I was left with incomplete experiments and an upcoming deadline to present my work. Independent research for the chemical and biological engineering (CBE ) department is only one semester long, and I spent most of the first half of the semester doing literature review, planning experiments and learning lab techniques. With only eight weeks left before my final paper and presentation deadline, I worried about the possibility of having to change my entire research topic into something that could be completed remotely. However, along with the lead researcher of the lab, or principal investigator (PI), and graduate student mentor, we developed a plan to easily transition the project I had already been working on into a remote project. In this post, I will give tips on how to conduct laboratory research remotely.

Conducting laboratory-heavy research remotely can be challenging. However, due to the collaborative nature of research, a laboratory project can successfully be modified to be conducted remotely.
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Preparing for a Lab-Heavy Semester

As I began choosing my courses for next semester, I knew I had to take CBE core lab, as this is a requirement for the concentration during the spring semester of junior year. In addition, I was really excited about conducting independent work in a new bioengineering lab, which I am hoping will be the lab that I stay in for my senior thesis. With both 7 hours of core lab per week and an expectation of 20 hours of independent work per week, I know I will be spending a lot of time in the lab next semester, so I have started to prepare for that. If you are also taking core lab while doing independent work, or if you are enrolled in multiple lab-courses, such as chemistry, molecular biology and physics at the same time, you will likely need to plan ahead. In this post, I will offer tips on how to prepare for a lab-heavy semester: 

Princeton University, Office of Communications, Denise Applewhite (2013)
Lab hours can quickly add up, especially if you are not organized with your time. Begin planning your schedule for a lab-heavy semester early in order to set your own expectations for you project.
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How to Schedule a One-on-One with a Professor

As a sophomore planning on declaring in neuroscience, I’ve been wondering a lot about the types of research projects neuroscience majors do for their independent work and senior thesis. To get a better feel for these projects, I’ve been reaching out to neuroscience faculty, sometimes via cold emails – a task made easier with the help of this post. However, I recently wanted to reach out to one of my current neuroscience professors in particular, both to hear more about his undergraduates’ research projects and to develop a better relationship with him.

Building positive relationships with your professors is important and rewarding. It’s easy to regard getting to know professors as a purely professional opportunity: that is, for the purposes of soliciting a recommendation or finding a lab position. However, this process is rewarding in other equally important ways: for example, I enjoy when professors explain the trajectory of their own careers, since it has helped me clarify my own academic and extracurricular interests. Often times my meetings with professors have developed into personally meaningful friendships that I hope will extend beyond my time at Princeton.

A Coffee Chat at Prospect House

Although most of us would agree its important to build relationships with professors, it can be more difficult to know how to accomplish that. How do you approach a professor? Where and when do you meet? And what do you actually say to them? All of these questions ran through my head as I wondered how I would go about meeting the neuroscience professor I mentioned above. Meeting professors can be nerve-wracking – that’s why I’ve put together the eight tips I used that streamlined the process.

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