Into the Unknown

Reflection on my personal experience tackling a new research paradigm

Yubi Mamiya presenting her findings on "Clinical trial simulation of ensitrelvir for SARS-CoV-2" to the Fred Hutchinson Cancer Center Infectious Disease Sciences Department.
Yubi Mamiya presenting her findings on “Clinical trial simulation of ensitrelvir for SARS-CoV-2” to the Fred Hutchinson Cancer Center Infectious Disease Sciences Department.

I’ve always believed in challenging myself to learn new methodologies and explore new fields in my research. Yet, there’s a fine balance between tackling a new challenge and feeling over your head. Reflecting on my past summer conducting a project in a completely new research paradigm, I wanted to take a moment to share my experience in the hopes of encouraging other students to be unafraid to undertake novel endeavors.

I had the life-changing opportunity to research the dose-response of the oral antiviral ensitrelvir for treating mild to moderate symptoms of SARS-CoV-2 with the Schiffer Lab starting this past June as an intern in the Fred Hutchinson Cancer Center Infectious Disease Sciences Internship Program. This project employed a very different application of my interests in healthcare and computer programming than I’d ever done before. Wide-eyed with amazement and curiosity, I delved into the fields of pharmacology, clinical trials, mathematical modeling, infectious diseases, and computational simulations. I remember learning about my project goals for the first time and thinking: “Wow, there are thousands of other students who would make a much better intern on this project”. This overwhelming imposter syndrome is something that I’ve often struggled with during my past research experiences when walking into new fields for the first time. But, thanks to the incredible mentorship of the Schiffer Lab and the tips that they shared with me, I overcame this fear and was able to grow into a more interdisciplinary and confident researcher this summer. I hope to pass on this same inspiration to other students here.

Continue reading Into the Unknown

Choosing A Lab: To Stay or To Go?

Photo meant to show students in a laboratory setting.
Students collaborating in a molecular biology laboratory. Photo credit: Matt Raspanti.

Many students at Princeton spend their summers exploring a research project or a lab internship in their field of interest. But what’s next? Maybe you really enjoyed your experience and wanted to continue. Then, you come across the question: should I stay in the same lab or join a different lab? 

This was the question I pondered when entering my sophomore year. I had an incredible summer experience as an High Meadows Environmental Institute intern in the Sigman Research Laboratory in the summer of 2023. I worked on a project that enabled my exploration of biogeochemical reconstruction via an investigation of the marine environment during a historical mass extinction through the use of a biological proxy known as foraminifera. But, where did I want to go from there? If you’re in a similar position, here are some things to keep in mind! 

Continue reading Choosing A Lab: To Stay or To Go?

Exploring Memory: My First-Year Research Experience

The picture shows Dr. Augustin Hennings and I in the MRI control room on the C Level of Princeton Neuroscience Institute. We were monitoring the screens in one of the pilot scans.
Dr. Augustin Hennings and I in the MRI control room, C Level, PNI

It felt a little odd to begin an email with, “I wrote about your lab in my application to Princeton!” but it was the truth. Since high school, I had been fascinated by memory and its profound effects on shaping our lives, which motivated me to pursue a degree in neuroscience. Professor Kenneth Norman’s work in the Princeton Computational Memory Lab captured my attention while I was exploring Princeton’s resources for my application essays. I wrote about how I wanted to be a part of the lab and study human memory, specifically focusing on how the brain and mind can overcome the emotional consequences of trauma-based memories. After arriving at Princeton, I had been eagerly awaiting the right time to reach out to Professor Norman about getting involved in his research.

Continue reading Exploring Memory: My First-Year Research Experience

Surf’s Up: A Guide to Internet Surfing, and other Assorted Browsing Research Skills

This image depicts a Google search of "What is research," which symbolizes the purpose of this post—i.e. figuring out how to research online.
What is research? Perhaps we can ask the Internet…

If you’re anything like me, you first thought that “research” essentially amounted to surfing the Internet. Back in the glory days of middle school, “research” meant the rewarded privilege of getting to use the laptop carts, productively using class time on googling information about our various project topics (and definitely not secretly playing games). Now, as the mature, worldly college student you now are, perhaps you think you know better. “True” academic research, the clever reader now knowingly tells themselves, is historians dusting through archival documents and scientists mixing frothy chemicals in the lab. 

Yet there’s a missing part here: a crucial element that takes us back to our elementary and middle days of excited googling. To make any significant intellectual contribution to any field, one first has to understand the current state of knowledge in that same field. To borrow the term favored by the Writing Program, we need to understand the scholarly conversation. How do we know if we’re making a contribution to something, if we don’t understand what that something is? Understanding the current state of research in a given field is a crucially important skill—really, a prerequisite—for conducting your own effective research in that field. 

Continue reading Surf’s Up: A Guide to Internet Surfing, and other Assorted Browsing Research Skills

Mentorship Matters: A Summer of Research and Growth

This image shows a lab technician pipetting a clear solution into an another orange-colored solution inside a fume hood in a lab
Photo of a chem-bioengineering lab, photo credit to Iris Rubinstein.

When I first walked into the lab this summer, I thought research was all about running experiments and gathering data. What I didn’t expect was how much the people around me—the mentorship and the shared triumphs and failures—would shape so much of my learning and how I view scientific research. 

Starting a research position at a bioengineering lab over the summer was really intimidating for me, especially as an undergraduate. At the start, I felt like the most inexperienced person in a room full of graduate students, postdocs, and faculty who seem to have it all figured out. Although I’ve learned or at least seen a lot of the quantitative and qualitative components in my Chemical and Biological Engineering course, I did not have much hands-on experience and critical thinking that comes with actually doing experiments. That’s when I realized how big of a role a mentor plays.

Continue reading Mentorship Matters: A Summer of Research and Growth

Bridging Research and Political Change

Spotlight on the Summer Internship Project of Princeton Politics Junior Mai Kasemsawade

Mai standing in front of a stage in the Malaysian parliament.
Mai Kasemsawade at the All-Party Parliamentary Group Malaysia for Political Financing meeting at the Malaysian Parliament, which she helped to host with The Institute for Democracy and Economic Affairs.

Many students walk into Princeton intending to change the world, Mai Kasemsawade ’26 is an extraordinary example of how one’s summer research can kickstart global political change. This past summer, Mai worked within the The Institute for Democracy and Economic Affairs in Kuala Lumpur, Malaysia as an intern in the Princeton International Internship Program. She connected her interests in political science research and data science to pursue an ambitious project in advancing Malaysia’s laws on funding for political parties in order to encourage a more democratic political scene. Her experience meeting with Malaysian government leaders, hosting a political engagement workshop, writing articles on critical policy, and conducting interdisciplinary research exemplifies the multitude of eye-opening opportunities that a research experience can offer!

Continue reading Bridging Research and Political Change

Research Insights Series: An Interview with Claire F. Gmachl

Claire F. Gmachl Headshot
Claire F. Gmachl stands at the forefront of groundbreaking research in mid-infrared photonics as the Eugene Higgins Professor of Electrical Engineering at Princeton University and the Head of Whitman College. She also serves as the Associate Chair of the Department of Electrical and Computer Engineering. With her expertise in semiconductor devices and photonics, Professor Gmachl delves into the realms of quantum-cascade lasers and beyond.

As a student surrounded by peers working on their junior papers or senior theses, as well as constantly hearing about groundbreaking faculty research, I came to seek a way to better engage with the research around me, and to synthesize current research and processes to bring insights to others. I decided to create a series of research insights, interviewing faculty and students, to learn more about their research topics, their personal research process and interests, as well as the potential implications from their findings.

In this article, I’m excited to have had the opportunity to interview Professor Claire Gmachl, who has also previously taught me in EGR 151: Foundations of Engineering: Mechanics, Energy, and Waves, the first physics course in the Engineering Sequence. In our interview, Professor Gmachl graciously shared insights into her research journey, shedding light on the multifaceted landscape of mid-infrared photonics and semiconductor devices.

Continue reading Research Insights Series: An Interview with Claire F. Gmachl

A Guide to Presentation

Have a presentation for one of your courses and unsure where to start? Or maybe you need to present for a research symposium? During your undergraduate years, you will come across many times when you may have to give a presentation to present your research for coursework or perhaps for an individual research pursuit. Here are some tips to help you present easily and effectively! 

individual giving a presentation to an audience
Give the most nerve-free presentation with these tips!
Continue reading A Guide to Presentation

Applying to Summer Programs

Quincy Monday ‘23 sitting in a chair working on his laptop in the lobby of New College West
Fortunately, if you’re stressed out trying to write all of these summer program applications, Princeton has plenty of comfortable study spaces to be working, like Quincy Monday ’23 in the lobby of NCW. Photo Credits: Dan Komoda (2023)

Applying to summer programs can seem like a daunting task when you may not even know what you want to do next summer. The busyness of the semester certainly hasn’t created a ton of time to be thinking about these things! Fortunately, winter break is a great time to work on applications to summer programs, as many of the earlier applications are often due early in the year. Having prepared them beforehand can ease a lot of stress, since the middle of the spring semester isn’t the most convenient time to be starting these applications. These timelines can vary by field, so it could be a bit different based on the type of program you are applying to—the career center has a great timeline of internship recruitment that is sorted by field so you can see the differences. Regardless, it’s great to work on these during the break when you don’t have courses.

You may be looking for something far away, here in Princeton, an industry internship at a company, or a research program at a university. Regardless of if you know exactly what you want to do or still aren’t sure, here are some tips to help you sort through this process.

Continue reading Applying to Summer Programs

Why Internships in Global Health?

2024 Program Applications Are Open!

7 lab members in a Zoom meeting
Dr. Lim’s lab during my summer internship with the University of Malaysia for the 2023 Princeton Internships in Global Health.

The Global Health Program hosts a wide variety of research internships on global health topics each summer. They provide a fully-funded experience for students of all class years and backgrounds to explore urgent health issues in regions all around the world. This eye-opening summer will help you learn about the differences in healthcare access and treatment globally, and contribute to impactful solutions. I had the incredible opportunity to conduct research and data analysis on Type II Diabetes treatment in Malaysia while interning at the University of Malaysia for the 2023 Internships in Global Health Program. Here are a few of the biggest takeaways and highlights of my internship so that you can get excited about the 2024 program!

Continue reading Why Internships in Global Health?