Exploring Memory: My First-Year Research Experience

The picture shows Dr. Augustin Hennings and I in the MRI control room on the C Level of Princeton Neuroscience Institute. We were monitoring the screens in one of the pilot scans.
Dr. Augustin Hennings and I in the MRI control room, C Level, PNI

It felt a little odd to begin an email with, “I wrote about your lab in my application to Princeton!” but it was the truth. Since high school, I had been fascinated by memory and its profound effects on shaping our lives, which motivated me to pursue a degree in neuroscience. Professor Kenneth Norman’s work in the Princeton Computational Memory Lab captured my attention while I was exploring Princeton’s resources for my application essays. I wrote about how I wanted to be a part of the lab and study human memory, specifically focusing on how the brain and mind can overcome the emotional consequences of trauma-based memories. After arriving at Princeton, I had been eagerly awaiting the right time to reach out to Professor Norman about getting involved in his research.

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2024 ReMatch+ Program

Get excited for this hands-on research opportunity: incredible 2023 undergraduate projects and AY23-24 fall events

Undergraduate student wearing a lab coat and lab glasses observing a vial of neon green solution in a chemistry lab
First-year and second-year undergraduate students learn and participate in research experiments directly related to their fields of interest for their summer research project

ReMatch+ is an incredible summer research program for first-year and second-year undergraduate students at Princeton. Launched in 2014, the program connects undergraduate students with dedicated, knowledgeable Princeton graduate students and postdoctoral fellows working across a diverse range of disciplines. Each year, ReMatch provides fellowship funding for joint summer research projects and mentorship between undergraduates and graduate students/postdoctoral fellows. Sign-ups for interested students and fall events are currently open; I encourage you to join the interest list to learn more about this incredible opportunity here. Here is a sample of some of the 2023 summer projects conducted by students with various interests and experiences to help you gain a sense of the breadth of opportunities provided by ReMatch.

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A Budding Field: Finding Opportunities in Psychedelic Research

The logo for the Princeton Science of Psychedelics Club. A large three-dimensional ring with blue radiating ovals.
The logo for Princeton’s Science of Psychedelics Club (PSPC), a student-lead organization seeking to educate students about psychedelics, discuss current trends in psychedelic research, and provide opportunities to other students interested in pursuing psychedelic research. If interested in joining, contact PSPC@princeton.edu or President Camilla Strauss ’23 for more information.

One goal for any budding researcher is to see their work have a tangible public impact. But, with endless hours spent in a lab or hunched over a computer, there are times where research can feel abstract or removed from reality. Neuroscience, in particular, faces this stereotype. True, many (including myself) believe that neuroscience holds the key to understanding our conscience and, by extension, our modern predicament. But the question remains: where can an aspiring neuroscientist find the life-altering research they seek?

Ironically, the answer might just lie in reality-altering substances. From neuroscience to public policy, psychedelics is a budding topic across many different fields of research. While Princeton itself is yet to enter the field, the Princeton Science of Psychedelics Club (PSPC) serves as the hub for all students interested in this emerging field. I sat down with PSPC and senior Neuroscience Major President Camilla Strauss to talk about how students interested in psychedelics research could learn more. 

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A Quick Crash Course in Statistics: Part 1

In PSY/NEU 338, From Animal Learning to Changing People’s Minds, my group recently presented our capstone project for the course: we researched irrationality, trying to understand when humans make irrational decisions, how that is implemented in the brain, and if certain things might actually be incorrectly labeled as ‘irrational’. Our emotions are a leading example: although some call them irrational, in practice, they play a key role in fine-tuning our decision-making and reasoning abilities. When you’re happy, for example, everything might be going more positively than expected. Your mood is thus encouraging you to continue the behaviors that led to those rewards, since that positive trend might continue (for a neuroscientific discussion of this topic, see this paper).

To demonstrate this phenomenon first-hand, we had students in the class play what is known as the Ultimatum Game:

You are the proposer. You have been given $100. You are tasked with splitting your money with a stranger, the responder. If the responder accepts the split that you propose, you both keep the money after the game ends. If the responder does not accept, no one keeps the money.

The question: how much money do you decide to offer the responder?

After reading this, students had five seconds to provide their answer. They were then asked to report their mood. The question we wanted to answer was simple:

Is the amount of money people offered statistically different between those who reported “positive” versus “negative” moods?

In this post, I’ll explain some of the basic statistics I used to formally answer this question, bolding some key terms in the field along the way. In my next post, I’ll walk through the programming aspect for visualizing those statistics. 

In Google Spreadsheet, I calculated the mean dollar amount for the “positive” and “negative” categories, equaling $32.2 and $66 respectively. The “equals” sign indicates a function, and D51:D55 corresponds to the cells containing the data for the “positive” category.
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What to do when Courses Require Instructor Permission

It’s that time of year again: everyone is spending endless amounts of time browsing and discussing the available spring courses with their friends, advisers, and mentors. The buildup is for good reason: it’s important to put together a balanced, enjoyable course schedule (for tips on how to go about doing that, check out this post).

I’ve personally had my eye on NEU 350, the neuroscience major requirement known for teaching data analysis techniques and lab procedures. Thus far in my Princeton career, I’ve learned a lot about theoretical methods within the discipline, but I’ve yet to actually apply those methods myself and work with real data. I wanted to take the class to learn these skills and broaden my understanding of what actual work within the neurosciences looks like.

However, I noticed under the “Prerequisites and Restrictions” header of the course on the registrar website that sophomores need permission from the Instructor to take the course. I found this odd considering that many sophomores are enrolled in NEU 314, a class that is typically taken by neuro majors the semester before NEU 350. The need for instructor permission felt intimidating to say the least, and in this post, I’ll share a few steps I took to learn more about NEU 350 and whether or not I should take it this spring.

An example of the brain-wave data that gets analyzed in NEU 350

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45 Days in the Life of a Researcher: An Invaluable Summer

The developmental social neuroscience lab studies how neural changes promote social, emotional, and cognitive development

As early as November of my freshman year, I remember hearing conversations around campus about summer plans. These conversations were not about the anticipation of vacation and relaxation, but rather the frantic and stressful search for the perfect summer opportunity to pad their resumes. It was safe to say that I was freaking out.

But this pressure motivated me to learn about my options, which ultimately allowed me to further explore my interests and participate in an incredibly rewarding research opportunity. After many meetings with my amazing academic advisers and career advisers at Career Services, I secured a position as a research assistant at a developmental neuroscience lab at UNC Chapel Hill.

This position consisted of nine consecutive weeks of unpaid, nine to five workdays, and the occasional shift on evenings and weekends. Sound draining? Yes, but I loved every second of it. Don’t get me wrong, it was a lot of work. But what was so enlightening about the experience was the fact that I actually enjoyed doing the work. I found something I was passionate about and I had the opportunity to engage with it every single day.

The first day was a blur—meeting everyone in the lab, getting familiar with the lab space, moving into my office (my own office!!!), and running around campus collecting my various parking permits and ID badges. After taking care of these logistical details, I hit the ground running.

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